STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFK40620.1RES domain-containing protein. (217 aa)    
Predicted Functional Partners:
SFK40639.1
Hypothetical protein.
 
     0.952
SFJ85391.1
DNA helicase-2 / ATP-dependent DNA helicase PcrA.
  
 
 0.946
SFK32128.1
DNA-binding transcriptional regulator, MerR family.
  
 
 0.835
SFJ54554.1
DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...]
  
 
 0.833
truB
tRNA pseudouridine55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
   
 
  0.816
SFJ56357.1
Hypothetical protein.
  
     0.772
SFK25471.1
Hypothetical protein.
 
     0.771
SFJ76406.1
Hypothetical protein.
  
     0.766
SFJ52584.1
Hypothetical protein.
  
     0.765
SFJ56547.1
Hypothetical protein.
  
     0.765
Your Current Organism:
Amycolatopsis sacchari
NCBI taxonomy Id: 115433
Other names: A. sacchari, Amycolatopsis sacchari Goodfellow et al. 2001, CIP 107029, DSM 44468, JCM 11272, KCTC 9863, NBRC 100339
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.