node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFI87073.1 | SFK73370.1 | SAMN05421835_1029 | SAMN05421835_13111 | Branched-chain amino acid aminotransferase. | Acetolactate synthase, large subunit. | 0.561 |
SFI87073.1 | SFK73391.1 | SAMN05421835_1029 | SAMN05421835_13112 | Branched-chain amino acid aminotransferase. | Acetolactate synthase, small subunit. | 0.825 |
SFI87073.1 | SFK73509.1 | SAMN05421835_1029 | SAMN05421835_13118 | Branched-chain amino acid aminotransferase. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.935 |
SFI87073.1 | ilvC | SAMN05421835_1029 | SAMN05421835_13113 | Branched-chain amino acid aminotransferase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.871 |
SFI87073.1 | ilvD | SAMN05421835_1029 | SAMN05421835_12530 | Branched-chain amino acid aminotransferase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.974 |
SFI87073.1 | ilvD-2 | SAMN05421835_1029 | SAMN05421835_1314 | Branched-chain amino acid aminotransferase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.961 |
SFI87073.1 | leuA | SAMN05421835_1029 | SAMN05421835_108241 | Branched-chain amino acid aminotransferase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.984 |
SFI87073.1 | leuC | SAMN05421835_1029 | SAMN05421835_13721 | Branched-chain amino acid aminotransferase. | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.789 |
SFI87073.1 | leuD | SAMN05421835_1029 | SAMN05421835_13722 | Branched-chain amino acid aminotransferase. | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.547 |
SFI87073.1 | panB | SAMN05421835_1029 | SAMN05421835_116159 | Branched-chain amino acid aminotransferase. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.909 |
SFK73370.1 | SFI87073.1 | SAMN05421835_13111 | SAMN05421835_1029 | Acetolactate synthase, large subunit. | Branched-chain amino acid aminotransferase. | 0.561 |
SFK73370.1 | SFK73391.1 | SAMN05421835_13111 | SAMN05421835_13112 | Acetolactate synthase, large subunit. | Acetolactate synthase, small subunit. | 0.998 |
SFK73370.1 | SFK73509.1 | SAMN05421835_13111 | SAMN05421835_13118 | Acetolactate synthase, large subunit. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.755 |
SFK73370.1 | ilvC | SAMN05421835_13111 | SAMN05421835_13113 | Acetolactate synthase, large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
SFK73370.1 | ilvD | SAMN05421835_13111 | SAMN05421835_12530 | Acetolactate synthase, large subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.888 |
SFK73370.1 | ilvD-2 | SAMN05421835_13111 | SAMN05421835_1314 | Acetolactate synthase, large subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.868 |
SFK73370.1 | leuA | SAMN05421835_13111 | SAMN05421835_108241 | Acetolactate synthase, large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.929 |
SFK73370.1 | leuC | SAMN05421835_13111 | SAMN05421835_13721 | Acetolactate synthase, large subunit. | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.822 |
SFK73370.1 | leuD | SAMN05421835_13111 | SAMN05421835_13722 | Acetolactate synthase, large subunit. | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.856 |
SFK73391.1 | SFI87073.1 | SAMN05421835_13112 | SAMN05421835_1029 | Acetolactate synthase, small subunit. | Branched-chain amino acid aminotransferase. | 0.825 |