STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKA48500.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (606 aa)    
Predicted Functional Partners:
AKA47818.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.999
AKA47747.1
DNA-directed RNA polymerase subunit D; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.993
AKA47764.1
DNA-directed RNA polymerase subunit H; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.991
AKA48469.1
DNA-directed RNA polymerase subunit P; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.990
AKA47963.1
Transcription factor; TFIID; binds specifically to the TATA box and functions in transcription; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.988
AKA47763.1
DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.986
rpoK
DNA-directed RNA polymerase subunit K; Promotes RNAP assembly or increases stability; similar to eukaryotic RPB6 and bacterial subunit omega; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.986
AKA48644.1
DNA-directed RNA polymerase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.981
AKA48963.1
Flap endonuclease-1; FEN-1; Rad2; similar to eukaryotic enzymes; endonuclease that cleave the 5'overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'end of a downstream Okazaki fragment; as 5'endo-/exonuclease and 5'pseudo-Y-endonuclease activities; cleaves the junction between single and double-stranded regions of flap DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.980
tfb
Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter; responsible for recruiting RNA polymerase II to the pre-initiation complex; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.963
Your Current Organism:
uncultured archaeon
NCBI taxonomy Id: 115547
Other names: u. archaeon, uncultured Archaea archaeon, uncultured archaeoote
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