Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AKA49060.1NAD synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)    
Predicted Functional Partners:
AKA48967.1
Nicotinamide-nucleotide adenylyltransferase; Catalyzes the formation of NAD+ from nicotinamide ribonucleotide and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.926
ppnK
Inorganic polyphosphate kinase; Catalyzes the phosphorylation of NAD to NADP; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.896
AKA48998.1
Nicotinate phosphoribosyltransferase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.862
AKA49004.1
NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.831
AKA49059.1
Sodium:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.831
AKA49002.1
NAD(P) transhydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.828
AKA49358.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.821
AKA49003.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.811
AKA47908.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.803
AKA47777.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.722
Your Current Organism:
uncultured archaeon
NCBI taxonomy Id: 115547
Other names: u. archaeon, uncultured Archaea archaeon, uncultured archaeoote
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