STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (457 aa)    
Predicted Functional Partners:
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
  
 0.872
recX
Recombinase RecX; Modulates RecA activity; Belongs to the RecX family.
  
  
 0.861
selD
Hypothetical protein; Synthesizes selenophosphate from selenide and ATP.
       0.772
KHJ49919.1
tRNA 2-selenouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SelU family.
       0.772
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
   
    0.766
KHJ49916.1
Copper resistance lipoprotein NlpE; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.707
KHJ51442.1
DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.678
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
  
 0.663
KHJ50437.1
Recombination and repair protein; May be involved in recombinational repair of damaged DNA.
  
   
 0.645
hisC
Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
 0.637
Your Current Organism:
Halomonas hydrothermalis
NCBI taxonomy Id: 115561
Other names: ATCC BAA-800, CECT 5814, DSM 15725, H. hydrothermalis, Halomonas hydrothermalis Kaye et al. 2004, Halomonas sp. Slthf2.1878c, strain Slthf2
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