STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDRG_14131TPR_REGION domain-containing protein. (329 aa)    
Predicted Functional Partners:
SDRG_09329
ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]
   
 0.810
SDRG_13845
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 0.776
SDRG_05575
Uncharacterized protein.
    
 0.766
SDRG_01579
TPR_REGION domain-containing protein.
    
 0.765
SDRG_10060
Uncharacterized protein.
    
 0.765
SDRG_17250
Uncharacterized protein.
    
 0.764
SDRG_01703
Uncharacterized protein.
    
 0.764
SDRG_05491
Uncharacterized protein.
    
 0.764
SDRG_13494
ANAPC5 domain-containing protein.
    
 0.763
SDRG_14185
HATPase_c domain-containing protein.
   
 0.763
Your Current Organism:
Saprolegnia diclina
NCBI taxonomy Id: 1156394
Other names: S. diclina VS20, Saprolegnia declina VS20, Saprolegnia diclina VS20
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