STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DBT_0115Pyruvate carboxyl transferase subunit B. (678 aa)    
Predicted Functional Partners:
DBT_0114
Biotin operon repressor / Biotin-protein ligase.
 
 
 0.997
DBT_0116
Biotin carboxylase of acetyl-CoA carboxylase.
 
 0.996
DBT_0366
Biotin carboxylase of acetyl-CoA carboxylase.
 
 0.982
DBT_0365
Acetyl-coenzyme A carboxyl transferase alpha chain.
 
 0.834
DBT_0607
2-oxoglutarate oxidoreductase, alpha subunit.
     
 0.790
DBT_1277
NADP-dependent malic enzyme.
   
 0.753
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 0.737
DBT_1747
Glutamate synthase [NADPH] large chain.
  
 
 0.737
DBT_0364
Hypothetical protein.
  
 
 0.640
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.635
Your Current Organism:
Dissulfuribacter thermophilus
NCBI taxonomy Id: 1156395
Other names: D. thermophilus, DSM 25762, Dissulfuribacter thermophilus Slobodkin et al. 2013, VKM B-2760, delta proteobacterium S69, strain S69
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