STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DBT_08785,10-methylenetetrahydrofolate reductase. (1042 aa)    
Predicted Functional Partners:
DBT_0876
Acetyl-CoA synthase corrinoid iron-sulfur protein, large subunit.
 
 0.999
DBT_0875
5-methyltetrahydrofolate:corrinoid iron-sulfur protein methyltransferase.
 
 0.998
DBT_0877
CO dehydrogenase/acetyl-CoA synthase, acetyl-CoA synthase subunit.
 
 0.998
DBT_1865
Hypothetical protein.
 
 0.998
DBT_0879
Methylene-tetrahydrofolate reductase C terminal.
 
 
 0.990
DBT_1356
Acetyl-CoA synthase corrinoid activation protein.
 
 
   0.962
DBT_0793
Acetyl-CoA synthase corrinoid activation protein.
 
 
   0.958
DBT_2067
Hypothetical protein.
 
 0.949
DBT_0011
Bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase.
 
 
0.935
folD
Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.930
Your Current Organism:
Dissulfuribacter thermophilus
NCBI taxonomy Id: 1156395
Other names: D. thermophilus, DSM 25762, Dissulfuribacter thermophilus Slobodkin et al. 2013, VKM B-2760, delta proteobacterium S69, strain S69
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