node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DBT_0254 | DBT_0687 | DBT_0254 | DBT_0687 | ATP-dependent DNA helicase UvrD/PcrA. | Excinuclease ABC subunit A. | 0.422 |
DBT_0254 | ligA | DBT_0254 | DBT_1876 | ATP-dependent DNA helicase UvrD/PcrA. | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.531 |
DBT_0254 | mutL | DBT_0254 | DBT_0604 | ATP-dependent DNA helicase UvrD/PcrA. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.672 |
DBT_0254 | polA | DBT_0254 | DBT_0536 | ATP-dependent DNA helicase UvrD/PcrA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.690 |
DBT_0254 | uvrB | DBT_0254 | DBT_0685 | ATP-dependent DNA helicase UvrD/PcrA. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.831 |
DBT_0254 | uvrC | DBT_0254 | DBT_1374 | ATP-dependent DNA helicase UvrD/PcrA. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.595 |
DBT_0590 | DBT_1098 | DBT_0590 | DBT_1098 | DNA polymerase III epsilon subunit. | Hypothetical protein. | 0.669 |
DBT_0590 | ligA | DBT_0590 | DBT_1876 | DNA polymerase III epsilon subunit. | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.706 |
DBT_0590 | polA | DBT_0590 | DBT_0536 | DNA polymerase III epsilon subunit. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.571 |
DBT_0590 | uvrC | DBT_0590 | DBT_1374 | DNA polymerase III epsilon subunit. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.646 |
DBT_0687 | DBT_0254 | DBT_0687 | DBT_0254 | Excinuclease ABC subunit A. | ATP-dependent DNA helicase UvrD/PcrA. | 0.422 |
DBT_0687 | polA | DBT_0687 | DBT_0536 | Excinuclease ABC subunit A. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.558 |
DBT_0687 | uvrB | DBT_0687 | DBT_0685 | Excinuclease ABC subunit A. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.993 |
DBT_0687 | uvrC | DBT_0687 | DBT_1374 | Excinuclease ABC subunit A. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.834 |
DBT_1098 | DBT_0590 | DBT_1098 | DBT_0590 | Hypothetical protein. | DNA polymerase III epsilon subunit. | 0.669 |
DBT_1098 | ligA | DBT_1098 | DBT_1876 | Hypothetical protein. | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.676 |
DBT_1098 | mutL | DBT_1098 | DBT_0604 | Hypothetical protein. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.400 |
DBT_1098 | polA | DBT_1098 | DBT_0536 | Hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.582 |
DBT_1098 | uvrB | DBT_1098 | DBT_0685 | Hypothetical protein. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.420 |
DBT_1098 | uvrC | DBT_1098 | DBT_1374 | Hypothetical protein. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.616 |