STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DBT_2289Hypothetical protein. (330 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.898
DBT_0059
Membrane-bound lytic murein transglycosylase D precursor.
   
 
 0.756
DBT_1729
PAS/PAC sensor hybrid histidine kinase.
   
 0.746
DBT_1286
Adenylate cyclase.
  
  
  0.719
DBT_0237
HD domain protein.
  
 
 0.702
DBT_2290
HD domain protein.
       0.697
DBT_0386
Multi-sensor hybrid histidine kinase.
   
 0.674
DBT_1695
Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s).
     
 0.666
DBT_1284
Iron dicitrate transport regulator FecR.
  
 
 0.660
DBT_1955
Sensor histidine kinase.
     
 0.622
Your Current Organism:
Dissulfuribacter thermophilus
NCBI taxonomy Id: 1156395
Other names: D. thermophilus, DSM 25762, Dissulfuribacter thermophilus Slobodkin et al. 2013, VKM B-2760, delta proteobacterium S69, strain S69
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.