STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SJZ37245.1Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. (262 aa)    
Predicted Functional Partners:
SJZ37210.1
Precorrin-2 C20-methyltransferase /cobalt-factor II C20-methyltransferase.
 
 
 0.997
SJZ37147.1
Cobalt-precorrin 5A hydrolase.
 
 
 0.994
SJZ37050.1
precorrin-6A reductase.
 
 
 0.990
SJZ37171.1
Precorrin-4/cobalt-precorrin-4 C11-methyltransferase.
 
 
 0.987
SJZ37120.1
Precorrin-3 methyltransferase.
 
 
 0.979
SJZ37308.1
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
 
 
 0.978
cbiD
cobalt-precorrin-5B (C1)-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.973
SJZ37262.1
precorrin-8X methylmutase.
 
  
 0.970
cbiA
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) /cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 
 0.960
SJZ37033.1
precorrin-6Y C5,15-methyltransferase (decarboxylating).
 
 
 0.953
Your Current Organism:
Geobacter thiogenes
NCBI taxonomy Id: 115783
Other names: ATCC BAA-34, G. thiogenes, Geobacter thiogenes (De Wever et al. 2001) Nevin et al. 2007, JCM 14045, Trichlorobacter thiogenes, Trichlorobacter thiogenes De Wever et al. 2001, strain K1
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