node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SKA10638.1 | SKA10687.1 | SAMN02745119_02662 | SAMN02745119_02669 | Periplasmic chaperone for outer membrane proteins Skp. | KDO2-lipid IV(A) lauroyltransferase. | 0.723 |
SKA10638.1 | SKA10726.1 | SAMN02745119_02662 | SAMN02745119_02670 | Periplasmic chaperone for outer membrane proteins Skp. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.575 |
SKA10638.1 | bamA | SAMN02745119_02662 | SAMN02745119_02661 | Periplasmic chaperone for outer membrane proteins Skp. | Beta-barrel assembly machine subunit BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.944 |
SKA10638.1 | fabZ | SAMN02745119_02662 | SAMN02745119_02437 | Periplasmic chaperone for outer membrane proteins Skp. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.443 |
SKA10638.1 | fabZ-2 | SAMN02745119_02662 | SAMN02745119_02664 | Periplasmic chaperone for outer membrane proteins Skp. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.847 |
SKA10638.1 | lpxA | SAMN02745119_02662 | SAMN02745119_02665 | Periplasmic chaperone for outer membrane proteins Skp. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.844 |
SKA10638.1 | lpxB | SAMN02745119_02662 | SAMN02745119_02668 | Periplasmic chaperone for outer membrane proteins Skp. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.759 |
SKA10638.1 | lpxD-2 | SAMN02745119_02662 | SAMN02745119_02663 | Periplasmic chaperone for outer membrane proteins Skp. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.894 |
SKA10638.1 | lpxK | SAMN02745119_02662 | SAMN02745119_02671 | Periplasmic chaperone for outer membrane proteins Skp. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.575 |
SKA10687.1 | SKA10638.1 | SAMN02745119_02669 | SAMN02745119_02662 | KDO2-lipid IV(A) lauroyltransferase. | Periplasmic chaperone for outer membrane proteins Skp. | 0.723 |
SKA10687.1 | SKA10726.1 | SAMN02745119_02669 | SAMN02745119_02670 | KDO2-lipid IV(A) lauroyltransferase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.994 |
SKA10687.1 | bamA | SAMN02745119_02669 | SAMN02745119_02661 | KDO2-lipid IV(A) lauroyltransferase. | Beta-barrel assembly machine subunit BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.705 |
SKA10687.1 | fabZ-2 | SAMN02745119_02669 | SAMN02745119_02664 | KDO2-lipid IV(A) lauroyltransferase. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.771 |
SKA10687.1 | lpxA | SAMN02745119_02669 | SAMN02745119_02665 | KDO2-lipid IV(A) lauroyltransferase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.949 |
SKA10687.1 | lpxB | SAMN02745119_02669 | SAMN02745119_02668 | KDO2-lipid IV(A) lauroyltransferase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.947 |
SKA10687.1 | lpxC | SAMN02745119_02669 | SAMN02745119_00815 | KDO2-lipid IV(A) lauroyltransferase. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.780 |
SKA10687.1 | lpxD-2 | SAMN02745119_02669 | SAMN02745119_02663 | KDO2-lipid IV(A) lauroyltransferase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.938 |
SKA10687.1 | lpxK | SAMN02745119_02669 | SAMN02745119_02671 | KDO2-lipid IV(A) lauroyltransferase. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.937 |
SKA10726.1 | SKA10638.1 | SAMN02745119_02670 | SAMN02745119_02662 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Periplasmic chaperone for outer membrane proteins Skp. | 0.575 |
SKA10726.1 | SKA10687.1 | SAMN02745119_02670 | SAMN02745119_02669 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | KDO2-lipid IV(A) lauroyltransferase. | 0.994 |