STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APU25183.1Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)    
Predicted Functional Partners:
APU24701.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
0.995
APU25182.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.993
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.992
APU25181.1
Septation inhibitor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.917
APU26890.1
RNA degradosome polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.880
eno
Phosphopyruvate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.876
lpqU
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.775
ppk2
Polyphosphate kinase 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.745
mazG
Nucleoside triphosphate hydrolase; Functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.723
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
 
  0.683
Your Current Organism:
Mycobacterium tuberculosis variant caprae
NCBI taxonomy Id: 115862
Other names: ATCC BAA-824, CIP 105776, M. tuberculosis variant caprae, Mycobacterium bovis subsp. caprae, Mycobacterium caprae, Mycobacterium tuberculosis subsp. caprae, strain gM-1, strain spc-1
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