STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UV8b_7529DNA repair protein rad32; Belongs to the MRE11/RAD32 family. (1279 aa)    
Predicted Functional Partners:
UV8b_1954
DNA repaire protein UVS6.
  
 0.999
UV8b_6081
Werner syndrome helicase.
  
 0.997
UV8b_1281
Serine/threonine-protein kinase tel-1; Belongs to the PI3/PI4-kinase family.
   
 0.989
UV8b_1383
Exonuclease.
   
 0.986
UV8b_3254
Ku70 protein.
   
 0.983
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.982
UV8b_7988
ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.
   
 0.980
UV8b_979
Protein kinase rad3; Belongs to the PI3/PI4-kinase family.
   
 0.974
UV8b_7951
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
   
 0.968
UV8b_7476
BRCT domain-containing protein.
   
 0.950
Your Current Organism:
Ustilaginoidea virens
NCBI taxonomy Id: 1159556
Other names: Claviceps virens, MAFF 240994, MAFF 240995, TNS:F-18423, U. virens, Villosiclava virens, Villosiclava virens (Y. Sakurai ex Nakata) E. Tanaka & C. Tanaka 2009
Server load: low (20%) [HD]