node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | UV8b_201 | A0A063BTT3 | A0A063C6Y0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Checkpoint protein; Belongs to the HUS1 family. | 0.900 |
FEN1 | UV8b_2557 | A0A063BTT3 | A0A063C4Z1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein RAD9. | 0.886 |
FEN1 | UV8b_3527 | A0A063BTT3 | A0A063BZH0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein. | 0.871 |
FEN1 | UV8b_4585 | A0A063BTT3 | A0A063BUS7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Putative replication factor C. | 0.924 |
FEN1 | UV8b_4728 | A0A063BTT3 | A0A063BZ26 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Cell cycle checkpoint protein RAD17. | 0.848 |
FEN1 | UV8b_5667 | A0A063BTT3 | A0A063BZA0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Activator 1 41 kDa subunit. | 0.936 |
FEN1 | UV8b_575 | A0A063BTT3 | A0A063CAL3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Activator 1 subunit 3. | 0.877 |
FEN1 | UV8b_6081 | A0A063BTT3 | A0A063BS81 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Werner syndrome helicase. | 0.999 |
FEN1 | UV8b_746 | A0A063BTT3 | A0A063CDC1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Activator 1 38 kDa subunit. | 0.943 |
FEN1 | UV8b_979 | A0A063BTT3 | A0A063C725 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | 0.834 |
UV8b_201 | FEN1 | A0A063C6Y0 | A0A063BTT3 | Checkpoint protein; Belongs to the HUS1 family. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.900 |
UV8b_201 | UV8b_2557 | A0A063C6Y0 | A0A063C4Z1 | Checkpoint protein; Belongs to the HUS1 family. | DNA repair protein RAD9. | 0.999 |
UV8b_201 | UV8b_3527 | A0A063C6Y0 | A0A063BZH0 | Checkpoint protein; Belongs to the HUS1 family. | DNA repair protein. | 0.978 |
UV8b_201 | UV8b_4585 | A0A063C6Y0 | A0A063BUS7 | Checkpoint protein; Belongs to the HUS1 family. | Putative replication factor C. | 0.982 |
UV8b_201 | UV8b_4728 | A0A063C6Y0 | A0A063BZ26 | Checkpoint protein; Belongs to the HUS1 family. | Cell cycle checkpoint protein RAD17. | 0.990 |
UV8b_201 | UV8b_5667 | A0A063C6Y0 | A0A063BZA0 | Checkpoint protein; Belongs to the HUS1 family. | Activator 1 41 kDa subunit. | 0.983 |
UV8b_201 | UV8b_575 | A0A063C6Y0 | A0A063CAL3 | Checkpoint protein; Belongs to the HUS1 family. | Activator 1 subunit 3. | 0.975 |
UV8b_201 | UV8b_6081 | A0A063C6Y0 | A0A063BS81 | Checkpoint protein; Belongs to the HUS1 family. | Werner syndrome helicase. | 0.990 |
UV8b_201 | UV8b_746 | A0A063C6Y0 | A0A063CDC1 | Checkpoint protein; Belongs to the HUS1 family. | Activator 1 38 kDa subunit. | 0.981 |
UV8b_201 | UV8b_979 | A0A063C6Y0 | A0A063C725 | Checkpoint protein; Belongs to the HUS1 family. | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | 0.934 |