node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | UV8b_2003 | A0A063BTT3 | A0A063C4Y7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Sister chromatid cohesion protein Eso1. | 0.810 |
FEN1 | UV8b_2349 | A0A063BTT3 | A0A063C616 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.998 |
FEN1 | UV8b_2472 | A0A063BTT3 | A0A063C3E4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Putative DNA polymerase delta subunit 2. | 0.958 |
FEN1 | UV8b_2653 | A0A063BTT3 | A0A063C5P4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase. | 0.990 |
FEN1 | UV8b_4585 | A0A063BTT3 | A0A063BUS7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Putative replication factor C. | 0.924 |
FEN1 | UV8b_4967 | A0A063BTT3 | A0A063BY75 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.906 |
FEN1 | UV8b_5667 | A0A063BTT3 | A0A063BZA0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Activator 1 41 kDa subunit. | 0.936 |
FEN1 | UV8b_575 | A0A063BTT3 | A0A063CAL3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Activator 1 subunit 3. | 0.877 |
FEN1 | UV8b_6081 | A0A063BTT3 | A0A063BS81 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Werner syndrome helicase. | 0.999 |
FEN1 | UV8b_746 | A0A063BTT3 | A0A063CDC1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Activator 1 38 kDa subunit. | 0.943 |
UV8b_2003 | FEN1 | A0A063C4Y7 | A0A063BTT3 | Sister chromatid cohesion protein Eso1. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.810 |
UV8b_2003 | UV8b_2349 | A0A063C4Y7 | A0A063C616 | Sister chromatid cohesion protein Eso1. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.999 |
UV8b_2003 | UV8b_2472 | A0A063C4Y7 | A0A063C3E4 | Sister chromatid cohesion protein Eso1. | Putative DNA polymerase delta subunit 2. | 0.792 |
UV8b_2003 | UV8b_2653 | A0A063C4Y7 | A0A063C5P4 | Sister chromatid cohesion protein Eso1. | DNA polymerase. | 0.924 |
UV8b_2003 | UV8b_4585 | A0A063C4Y7 | A0A063BUS7 | Sister chromatid cohesion protein Eso1. | Putative replication factor C. | 0.987 |
UV8b_2003 | UV8b_4967 | A0A063C4Y7 | A0A063BY75 | Sister chromatid cohesion protein Eso1. | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.599 |
UV8b_2003 | UV8b_5667 | A0A063C4Y7 | A0A063BZA0 | Sister chromatid cohesion protein Eso1. | Activator 1 41 kDa subunit. | 0.991 |
UV8b_2003 | UV8b_575 | A0A063C4Y7 | A0A063CAL3 | Sister chromatid cohesion protein Eso1. | Activator 1 subunit 3. | 0.987 |
UV8b_2003 | UV8b_6081 | A0A063C4Y7 | A0A063BS81 | Sister chromatid cohesion protein Eso1. | Werner syndrome helicase. | 0.986 |
UV8b_2003 | UV8b_746 | A0A063C4Y7 | A0A063CDC1 | Sister chromatid cohesion protein Eso1. | Activator 1 38 kDa subunit. | 0.991 |