STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UV8b_2349Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (913 aa)    
Predicted Functional Partners:
UV8b_5667
Activator 1 41 kDa subunit.
  
 0.999
UV8b_2003
Sister chromatid cohesion protein Eso1.
   
 0.999
UV8b_6081
Werner syndrome helicase.
  
 0.998
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.998
UV8b_4585
Putative replication factor C.
  
 0.998
UV8b_4967
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.998
UV8b_746
Activator 1 38 kDa subunit.
  
 0.998
UV8b_2653
DNA polymerase.
  
 0.996
UV8b_575
Activator 1 subunit 3.
  
 0.996
UV8b_2472
Putative DNA polymerase delta subunit 2.
   
 0.995
Your Current Organism:
Ustilaginoidea virens
NCBI taxonomy Id: 1159556
Other names: Claviceps virens, MAFF 240994, MAFF 240995, TNS:F-18423, U. virens, Villosiclava virens, Villosiclava virens (Y. Sakurai ex Nakata) E. Tanaka & C. Tanaka 2009
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