STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BNA5Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (505 aa)    
Predicted Functional Partners:
BNA1
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
  
 
 0.942
UV8b_6916
Indoleamine 2,3-dioxygenase subfamily.
   
 0.878
UV8b_2283
Putative L-kynurenine/alpha-aminoadipate aminotransferase.
   
 
 0.864
UV8b_1450
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
     
 0.856
UV8b_471
Kynurenine-oxoglutarate transaminase.
   
 
 0.828
UV8b_2108
Indoleamine 2,3-dioxygenase pyrrole 2,3-dioxygenase.
   
 0.801
UV8b_7754
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.
   
 
 0.776
UV8b_7249
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.
   
 
 0.776
UV8b_3738
Indoleamine 2,3-dioxygenase-like protein.
     
 0.776
katG
Catalase-peroxidase; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
 0.768
Your Current Organism:
Ustilaginoidea virens
NCBI taxonomy Id: 1159556
Other names: Claviceps virens, MAFF 240994, MAFF 240995, TNS:F-18423, U. virens, Villosiclava virens, Villosiclava virens (Y. Sakurai ex Nakata) E. Tanaka & C. Tanaka 2009
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