STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LFE_0163Hypothetical protein. (363 aa)    
Predicted Functional Partners:
LFE_0162
Hypothetical protein.
       0.773
LFE_2040
Putative histone deacetylase superfamily.
   
 0.626
LFE_0189
Putative DNA polymerase I.
 
 
 0.622
LFE_0164
Putative metallophosphoesterase.
  
 
 0.621
LFE_2365
Putative TPR-domain containing protein.
 
 0.576
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.567
LFE_2088
Putative SAM-dependent methyltransferase.
  
 
 0.508
LFE_0441
Hypothetical protein.
  
     0.493
LFE_0165
Hypothetical protein.
  
    0.487
LFE_2385
Putative parB-like partition protein; Belongs to the ParB family.
  
 
 0.454
Your Current Organism:
Leptospirillum ferrooxidans
NCBI taxonomy Id: 1162668
Other names: L. ferrooxidans C2-3, Leptospirillum ferrooxidans C2-3, Leptospirillum ferrooxidans str. C2-3, Leptospirillum ferrooxidans strain C2-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.