STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LFE_1745Isocitrate dehydrogenase, NADP-dependent. (416 aa)    
Predicted Functional Partners:
LFE_1805
Aconitate hydratase.
  
 0.986
LFE_0769
Isocitrate dehydrogenase.
 
0.947
LFE_1804
Citrate synthase.
 
 
 0.942
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
 
 
 0.908
LFE_0995
Glutamate synthase.
    
 0.887
LFE_1402
Putative aspartate aminotransferase.
   
 0.830
LFE_1142
Putative adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.828
argH
Putative argininosuccinate lyase.
     
 0.828
LFE_2320
Putative L-aspartate oxidase.
     
 0.811
nuoD
NADH dehydrogenase, subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
  
  
 0.798
Your Current Organism:
Leptospirillum ferrooxidans
NCBI taxonomy Id: 1162668
Other names: L. ferrooxidans C2-3, Leptospirillum ferrooxidans C2-3, Leptospirillum ferrooxidans str. C2-3, Leptospirillum ferrooxidans strain C2-3
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