STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOPH_07331Adenine phosphoribosyltransferase. (1159 aa)    
Predicted Functional Partners:
TOPH_08531
GMP synthase [glutamine-hydrolyzing].
  
 0.936
TOPH_00470
Adenosine kinase.
   
 0.881
TOPH_00414
Diphthine--ammonia ligase.
  
 
 0.877
TOPH_04768
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.869
TOPH_03143
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
    
 0.841
TOPH_04968
AMP deaminase.
   
 0.832
TOPH_05919
Bifunctional purine biosynthesis protein ADE17.
  
 0.821
TOPH_06434
Acyl-CoA dehydrogenase family member 10.
  
 
 0.817
TOPH_00565
Bifunctional epoxide hydrolase 2.
  
 
 0.817
TOPH_04012
Inosine-5'-monophosphate dehydrogenase; Belongs to the IMPDH/GMPR family.
  
 
 0.803
Your Current Organism:
Tolypocladium ophioglossoides
NCBI taxonomy Id: 1163406
Other names: Elaphocordyceps ophioglossoides CBS 100239, Elaphocordyceps ophioglossoides CBS100239, T. ophioglossoides CBS 100239, Tolypocladium ophioglossoides CBS 100239
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.