AFH42516.1 protein (Fervidicoccus fontis) - STRING interaction network

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

AFH42516.1

Putative Acetyltransferase. (229 aa)

Predicted Functional Partners:

AFH43224.1

0.871

AFH42298.1

0.781

AFH42249.1

0.530

AFH42543.1

0.504

AFH42406.1

0.491

AFH42821.1

0.488

AFH42515.1

0.485

AFH42387.1

0.478

AFH42906.1

0.470

AFH42626.1

0.447

Your Current Organism:

Fervidicoccus fontis

NCBI taxonomy Id: 1163730
Other names: Desulfurococcales archaeon Kam940, F. fontis Kam940, Fervidicoccus fontis DSM 19380, Fervidicoccus fontis Kam940, Fervidicoccus fontis str. Kam940, Fervidicoccus fontis strain Kam940

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFH42249.1	AFH42298.1	FFONT_0258	FFONT_0308	Putative dehydrogenase.	Glycosyltransferase, family 2.	0.612
AFH42249.1	AFH42516.1	FFONT_0258	FFONT_0526	Putative dehydrogenase.	Putative Acetyltransferase.	0.530
AFH42249.1	AFH42906.1	FFONT_0258	FFONT_0918	Putative dehydrogenase.	Udp-n-acetyl-d-mannosaminuronic acid dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	0.579
AFH42249.1	AFH43224.1	FFONT_0258	FFONT_1236	Putative dehydrogenase.	Aspartate aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.	0.877
AFH42298.1	AFH42249.1	FFONT_0308	FFONT_0258	Glycosyltransferase, family 2.	Putative dehydrogenase.	0.612
AFH42298.1	AFH42406.1	FFONT_0308	FFONT_0416	Glycosyltransferase, family 2.	Glycosyltransferase; GT4-domain containing protein; GT_MraY-like family.	0.565
AFH42298.1	AFH42516.1	FFONT_0308	FFONT_0526	Glycosyltransferase, family 2.	Putative Acetyltransferase.	0.781
AFH42298.1	AFH42626.1	FFONT_0308	FFONT_0636	Glycosyltransferase, family 2.	Glycosyltransferase, family 2; Two GT2 domains.	0.597
AFH42298.1	AFH42821.1	FFONT_0308	FFONT_0833	Glycosyltransferase, family 2.	Asparagine synthetase.	0.632
AFH42298.1	AFH42906.1	FFONT_0308	FFONT_0918	Glycosyltransferase, family 2.	Udp-n-acetyl-d-mannosaminuronic acid dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	0.606
AFH42298.1	AFH43224.1	FFONT_0308	FFONT_1236	Glycosyltransferase, family 2.	Aspartate aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.	0.799
AFH42387.1	AFH42406.1	FFONT_0397	FFONT_0416	DUF354 domain containing protein.	Glycosyltransferase; GT4-domain containing protein; GT_MraY-like family.	0.408
AFH42387.1	AFH42516.1	FFONT_0397	FFONT_0526	DUF354 domain containing protein.	Putative Acetyltransferase.	0.478
AFH42387.1	AFH42821.1	FFONT_0397	FFONT_0833	DUF354 domain containing protein.	Asparagine synthetase.	0.446
AFH42387.1	AFH42906.1	FFONT_0397	FFONT_0918	DUF354 domain containing protein.	Udp-n-acetyl-d-mannosaminuronic acid dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	0.423
AFH42406.1	AFH42298.1	FFONT_0416	FFONT_0308	Glycosyltransferase; GT4-domain containing protein; GT_MraY-like family.	Glycosyltransferase, family 2.	0.565
AFH42406.1	AFH42387.1	FFONT_0416	FFONT_0397	Glycosyltransferase; GT4-domain containing protein; GT_MraY-like family.	DUF354 domain containing protein.	0.408
AFH42406.1	AFH42516.1	FFONT_0416	FFONT_0526	Glycosyltransferase; GT4-domain containing protein; GT_MraY-like family.	Putative Acetyltransferase.	0.491
AFH42406.1	AFH42626.1	FFONT_0416	FFONT_0636	Glycosyltransferase; GT4-domain containing protein; GT_MraY-like family.	Glycosyltransferase, family 2; Two GT2 domains.	0.419
AFH42406.1	AFH42821.1	FFONT_0416	FFONT_0833	Glycosyltransferase; GT4-domain containing protein; GT_MraY-like family.	Asparagine synthetase.	0.561

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

13

average node degree:

2.36

avg. local clustering coefficient:

0.87

expected number of edges:

24

PPI enrichment p-value:

0.996

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009073

Aromatic amino acid family biosynthetic process

4 of 21

2.15

2.1

7.40e-05

GO:0009423

Chorismate biosynthetic process

3 of 7

2.5

1.95

0.00024

GO:0016310

Phosphorylation

6 of 269

1.22

1.14

0.00036

GO:0008652

Cellular amino acid biosynthetic process

4 of 122

1.39

0.92

0.0078

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004765

Shikimate kinase activity

3 of 3

2.87

2.35

5.20e-05

GO:0004764

Shikimate 3-dehydrogenase (NADP+) activity

3 of 3

2.87

2.35

5.20e-05

GO:0003866

3-phosphoshikimate 1-carboxyvinyltransferase activity

3 of 3

2.87

2.35

5.20e-05

GO:0003856

3-dehydroquinate synthase activity

3 of 3

2.87

2.35

5.20e-05

GO:0003855

3-dehydroquinate dehydratase activity

3 of 3

2.87

2.35

5.20e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2006

Mixed, incl. Phosphoprotein phosphatase activity, and Positive regulation of MAPK cascade

4 of 27

2.04

7.77e-05

CL:9675

Aromatic amino acid family biosynthetic process

3 of 15

2.17

1.85

0.00026

CL:2007

Mixed, incl. Regulation of NF-kappa B signaling, and Leucine-rich repeat

3 of 18

2.09

1.79

0.00031

CL:1907

Mixed, incl. MAPK signaling pathway - yeast, and GPCR downstream signalling

5 of 112

1.52

1.59

0.00011

CL:9680

Aromatic amino acid family biosynthetic process

2 of 10

2.17

1.08

0.0096

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00400

Phenylalanine, tyrosine and tryptophan biosynthesis

4 of 30

2.0

2.36

1.20e-05

map01230

Biosynthesis of amino acids

4 of 194

1.19

0.82

0.0072

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0057

Aromatic amino acid biosynthesis

2 of 9

2.22

0.9

0.0212

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01761

3-dehydroquinate synthase

2 of 2

2.87

1.15

0.0085

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR030960

3-dehydroquinate synthase domain

2 of 2

2.87

0.89

0.0252

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