STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFH42722.1Acyl-CoA synthetase (NDP forming), alpha subunit. (471 aa)    
Predicted Functional Partners:
AFH43201.1
Acyl-CoA synthetase (NDP forming), beta subunit.
 
 0.999
AFH42542.1
2-oxoacid:ferredoxin oxidoreductase alpha subunit.
  
 0.929
AFH42310.1
Acetyl-CoA acetyltransferase.
  
 
 0.919
AFH42596.1
acetyl-CoA C-acyltransferase 7.
  
 
 0.919
AFH42541.1
2-oxoacid:ferredoxin oxidoreductase, beta subunit.
    
 0.915
AFH42413.1
Acyl-CoA synthetase (NDP forming), alpha subunit.
  
  
 
0.907
AFH43012.1
Acyl-CoA synthetase (NDP forming), alpha subunit.
  
  
 
0.907
AFH43161.1
Acylphosphatase; Belongs to the acylphosphatase family.
    
 0.902
sucD
Succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
0.821
sucC
Succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.816
Your Current Organism:
Fervidicoccus fontis
NCBI taxonomy Id: 1163730
Other names: Desulfurococcales archaeon Kam940, F. fontis Kam940, Fervidicoccus fontis DSM 19380, Fervidicoccus fontis Kam940, Fervidicoccus fontis str. Kam940, Fervidicoccus fontis strain Kam940
Server load: low (22%) [HD]