STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UWK_00649PFAM: AAA domain; TIGRFAM: DNA sulfur modification protein DndD. (672 aa)    
Predicted Functional Partners:
sbcD
Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 0.980
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.964
UWK_00647
Putative sulfurtransferase DndC; PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: putative sulfurtransferase DndC.
   
 0.956
UWK_00651
Hypothetical protein; PFAM: AAA domain.
 
     0.938
UWK_03538
HRDC domain-containing protein; PFAM: HRDC domain; Family description; PIF1-like helicase.
  
 0.883
UWK_00650
DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: FtsK/SpoIIIE family.
 
   
 0.825
UWK_00648
Hypothetical protein.
       0.773
UWK_00652
Hypothetical protein.
       0.768
UWK_01214
ATP-dependent DNA helicase, RecQ family; PFAM: UvrD-like helicase C-terminal domain; Helicase conserved C-terminal domain; UvrD/REP helicase N-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family.
  
 0.698
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.525
Your Current Organism:
Desulfocapsa sulfexigens
NCBI taxonomy Id: 1167006
Other names: D. sulfexigens DSM 10523, Desulfocapsa sulfexigens DSM 10523, Desulfocapsa sulfexigens SB164P1, Desulfocapsa sulfexigens str. DSM 10523, Desulfocapsa sulfexigens strain DSM 10523
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