STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UWK_01346Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain. (488 aa)    
Predicted Functional Partners:
UWK_01347
PFAM: SNARE associated Golgi protein.
     0.993
UWK_01060
Hypothetical protein.
   
 0.915
UWK_01191
PFAM: Thioredoxin domain; TIGRFAM: small redox-active disulfide protein 2.
   
 0.915
UWK_02611
PFAM: Thioredoxin-like domain.
   
 0.915
UWK_03502
Hypothetical protein; PFAM: Thioredoxin domain.
   
 0.915
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.887
UWK_03539
Ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; N-terminal domain of ribose phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase.
   
 0.887
UWK_01974
Polyketide synthase family protein; PFAM: Acyl transferase domain; KR domain; Nitronate monooxygenase; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain.
  
 
 0.740
UWK_02586
Hypothetical protein; PFAM: Cytochrome b(N-terminal)/b6/petB.
   
  
 0.723
msrA
methionine-R-sulfoxide reductase/methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
  
 0.712
Your Current Organism:
Desulfocapsa sulfexigens
NCBI taxonomy Id: 1167006
Other names: D. sulfexigens DSM 10523, Desulfocapsa sulfexigens DSM 10523, Desulfocapsa sulfexigens SB164P1, Desulfocapsa sulfexigens str. DSM 10523, Desulfocapsa sulfexigens strain DSM 10523
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