STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UWK_01892Tyrosine lyase ThiH; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH. (368 aa)    
Predicted Functional Partners:
thiG
Putative enzyme of thiazole biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 0.999
UWK_01894
PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS.
  
    0.948
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.918
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
 0.912
UWK_01895
PFAM: ThiS-like ubiquitin; ThiF family; TIGRFAM: thiamine biosynthesis protein ThiF, family 2.
 
  
 0.887
UWK_02784
PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC.
 
  
 0.807
UWK_03070
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.724
UWK_01360
Serine phosphatase RsbU, regulator of sigma subunit; PFAM: Response regulator receiver domain; Stage II sporulation protein E (SpoIIE).
   
  
 0.705
UWK_03102
PFAM: Rod binding protein.
  
    0.648
UWK_01891
AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme.
       0.615
Your Current Organism:
Desulfocapsa sulfexigens
NCBI taxonomy Id: 1167006
Other names: D. sulfexigens DSM 10523, Desulfocapsa sulfexigens DSM 10523, Desulfocapsa sulfexigens SB164P1, Desulfocapsa sulfexigens str. DSM 10523, Desulfocapsa sulfexigens strain DSM 10523
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