STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UWK_02521PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (490 aa)    
Predicted Functional Partners:
UWK_03459
CheY-like receiver and HD-GYP domain-containing response regulator; PFAM: HD domain; Response regulator receiver domain.
 
    0.898
UWK_00157
PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
 
    0.861
UWK_02681
EAL domain-containing protein; PFAM: EAL domain; FHA domain.
  
 0.824
UWK_01738
PFAM: EAL domain; HAMP domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
    0.802
UWK_01067
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phospho-acceptor) domain; fused histidine kinase/response regulator receiver domain.
 
 
   0.776
UWK_02522
PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc).
       0.773
UWK_02523
Putative low-complexity protein; PFAM: Pentapeptide repeats (8 copies).
       0.773
UWK_01360
Serine phosphatase RsbU, regulator of sigma subunit; PFAM: Response regulator receiver domain; Stage II sporulation protein E (SpoIIE).
 
  
 0.765
UWK_03204
Putative domain HDIG-containing protein; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
 
 
   0.746
UWK_01079
Putative domain HDIG-containing protein; PFAM: HD domain; Response regulator receiver domain; TIGRFAM: uncharacterized domain HDIG.
 
    0.738
Your Current Organism:
Desulfocapsa sulfexigens
NCBI taxonomy Id: 1167006
Other names: D. sulfexigens DSM 10523, Desulfocapsa sulfexigens DSM 10523, Desulfocapsa sulfexigens SB164P1, Desulfocapsa sulfexigens str. DSM 10523, Desulfocapsa sulfexigens strain DSM 10523
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.