STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpBUnannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (409 aa)    
Predicted Functional Partners:
trpA
Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 0.999
trpF
Unannotated protein; Belongs to the TrpF family.
 
 0.999
trpC
Unannotated protein; Belongs to the TrpC family.
 
 0.999
trpD
Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.999
BU072_05435
Unannotated protein.
 
  
 0.993
BU072_05430
Unannotated protein.
 
 
 0.992
pabB
Unannotated protein.
 
  
 0.966
BU072_02635
Unannotated protein.
 
 
 0.948
ilvA
Unannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 0.900
glyA
Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.875
Your Current Organism:
Staphylococcus vitulinus
NCBI taxonomy Id: 1167632
Other names: S. vitulinus F1028, Staphylococcus vitulinus F1028, Staphylococcus vitulinus str. F1028, Staphylococcus vitulinus strain F1028
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.