STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (695 aa)    
Predicted Functional Partners:
W97_00019
Flavodoxin-like domain-containing protein.
 
0.909
W97_01664
Nitrate reductase.
 
  
   0.904
W97_08470
Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
    
 0.892
W97_02153
Uncharacterized protein.
     
 0.810
W97_03038
Cytochrome b5 heme-binding domain-containing protein.
     
 0.810
W97_04540
Uncharacterized protein.
     
 0.810
W97_01769
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.
    
 0.788
DRE2
Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...]
    
 0.755
W97_05601
PAPS_reduct domain-containing protein.
  
 
 0.731
W97_05389
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.725
Your Current Organism:
Coniosporium apollinis
NCBI taxonomy Id: 1168221
Other names: C. apollinis CBS 100218, Coniosporium apollinis CBS 100218, Coniosporium apollinis CBS 352.97
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