node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
W97_01238 | W97_01753 | R7YJM4 | R7YKV9 | Methylenetetrahydrofolate dehydrogenase (NAD+). | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.859 |
W97_01238 | W97_01912 | R7YJM4 | R7YLD7 | Methylenetetrahydrofolate dehydrogenase (NAD+). | Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. | 0.859 |
W97_01238 | W97_02040 | R7YJM4 | R7YLM7 | Methylenetetrahydrofolate dehydrogenase (NAD+). | Flavoprotein domain-containing protein. | 0.928 |
W97_01238 | W97_05682 | R7YJM4 | R7YWV2 | Methylenetetrahydrofolate dehydrogenase (NAD+). | FSH1 domain-containing protein. | 0.871 |
W97_01238 | W97_07526 | R7YJM4 | R7Z2E6 | Methylenetetrahydrofolate dehydrogenase (NAD+). | Thymidylate synthase. | 0.901 |
W97_01238 | W97_07540 | R7YJM4 | R7Z288 | Methylenetetrahydrofolate dehydrogenase (NAD+). | Pterin-binding domain-containing protein. | 0.444 |
W97_01238 | W97_07568 | R7YJM4 | R7Z284 | Methylenetetrahydrofolate dehydrogenase (NAD+). | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.871 |
W97_01238 | W97_07698 | R7YJM4 | R7Z319 | Methylenetetrahydrofolate dehydrogenase (NAD+). | FolB domain-containing protein. | 0.444 |
W97_01238 | W97_07970 | R7YJM4 | R7Z3H5 | Methylenetetrahydrofolate dehydrogenase (NAD+). | C-1-tetrahydrofolate synthase, cytoplasmic. | 0.939 |
W97_01753 | W97_01238 | R7YKV9 | R7YJM4 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Methylenetetrahydrofolate dehydrogenase (NAD+). | 0.859 |
W97_01753 | W97_01760 | R7YKV9 | R7YKU9 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | 0.806 |
W97_01753 | W97_01912 | R7YKV9 | R7YLD7 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. | 0.830 |
W97_01753 | W97_02040 | R7YKV9 | R7YLM7 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Flavoprotein domain-containing protein. | 0.910 |
W97_01753 | W97_05682 | R7YKV9 | R7YWV2 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | FSH1 domain-containing protein. | 0.856 |
W97_01753 | W97_07526 | R7YKV9 | R7Z2E6 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Thymidylate synthase. | 0.885 |
W97_01753 | W97_07540 | R7YKV9 | R7Z288 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Pterin-binding domain-containing protein. | 0.982 |
W97_01753 | W97_07568 | R7YKV9 | R7Z284 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.856 |
W97_01753 | W97_07698 | R7YKV9 | R7Z319 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | FolB domain-containing protein. | 0.842 |
W97_01753 | W97_07970 | R7YKV9 | R7Z3H5 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | C-1-tetrahydrofolate synthase, cytoplasmic. | 0.880 |
W97_01760 | W97_01753 | R7YKU9 | R7YKV9 | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.806 |