W97_03971 protein (Coniosporium apollinis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

W97_03971

Uncharacterized protein. (223 aa)

Predicted Functional Partners:

W97_01762

0.990

W97_07270

0.982

W97_06004

0.957

W97_00517

0.954

W97_03000

0.947

W97_00107

0.944

W97_05741

0.943

W97_06864

0.939

W97_02503

0.935

W97_04403

0.934

Your Current Organism:

Coniosporium apollinis

NCBI taxonomy Id: 1168221
Other names: C. apollinis CBS 100218, Coniosporium apollinis CBS 100218, Coniosporium apollinis CBS 352.97

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
W97_00107	W97_00517	R7YG61	R7YHL9	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.998
W97_00107	W97_02503	R7YG61	R7YNP7	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Uncharacterized protein.	0.999
W97_00107	W97_03000	R7YG61	R7YPE6	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Uncharacterized protein.	0.997
W97_00107	W97_03971	R7YG61	R7YSC3	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Uncharacterized protein.	0.944
W97_00107	W97_04403	R7YG61	R7YU34	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Uncharacterized protein.	0.999
W97_00107	W97_05741	R7YG61	R7YXV0	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Uncharacterized protein.	0.958
W97_00107	W97_06004	R7YG61	R7YY27	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Uncharacterized protein.	0.996
W97_00517	W97_00107	R7YHL9	R7YG61	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	0.998
W97_00517	W97_02503	R7YHL9	R7YNP7	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein.	0.999
W97_00517	W97_03000	R7YHL9	R7YPE6	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein.	0.996
W97_00517	W97_03971	R7YHL9	R7YSC3	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein.	0.954
W97_00517	W97_04403	R7YHL9	R7YU34	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein.	0.999
W97_00517	W97_05741	R7YHL9	R7YXV0	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein.	0.972
W97_00517	W97_06004	R7YHL9	R7YY27	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein.	0.999
W97_01762	W97_03971	R7YL42	R7YSC3	Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.	Uncharacterized protein.	0.990
W97_01762	W97_06864	R7YL42	R7Z1D6	Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.	0.818
W97_01762	W97_07270	R7YL42	R7Z1V8	Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.	Cytochrome c oxidase subunit XV assembly protein.	0.992
W97_02503	W97_00107	R7YNP7	R7YG61	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	0.999
W97_02503	W97_00517	R7YNP7	R7YHL9	Uncharacterized protein.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.999
W97_02503	W97_03000	R7YNP7	R7YPE6	Uncharacterized protein.	Uncharacterized protein.	0.998

page 1 of 4

Network Stats

number of nodes:

6

number of edges:

6

average node degree:

2

avg. local clustering coefficient:

0.85

expected number of edges:

5

PPI enrichment p-value:

0.431

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030956

glutamyl-tRNA(Gln) amidotransferase complex

3 of 4

2.28

1.95

0.00019

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:889

Amidase, and asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity

7 of 10

2.25

5.01

1.66e-11

CL:891

Styrene degradation

5 of 5

2.4

4.02

1.11e-08

CL:856

Mixed, incl. Glutathione metabolism, and Styrene degradation

8 of 31

1.81

3.82

3.71e-11

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

rrd00643

Styrene degradation

7 of 8

2.34

5.71

8.59e-13

rrd00627

Aminobenzoate degradation

5 of 9

2.15

3.55

3.41e-08

rrd00360

Phenylalanine metabolism

5 of 16

1.9

2.9

2.28e-07

rrd00330

Arginine and proline metabolism

5 of 21

1.78

2.6

5.49e-07

rrd00380

Tryptophan metabolism

4 of 14

1.86

2.33

6.82e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030956

glutamyl-tRNA(Gln) amidotransferase complex

4 of 5

2.3

2.76

4.13e-06

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01425

Amidase

3 of 4

2.28

1.66

0.00072

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036928

Amidase signature (AS) superfamily

3 of 4

2.28

1.45

0.0019

IPR023631

Amidase signature domain

3 of 4

2.28

1.45

0.0019

IPR020556

Amidase, conserved site

3 of 4

2.28

1.45

0.0019

IPR000120

Amidase

3 of 4

2.28

1.45

0.0019

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00882

Coenzyme A transferase

2 of 4

2.1

0.91

0.0199

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