STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Vbra_16594DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (864 aa)    
Predicted Functional Partners:
Vbra_1277
DUF1767 domain-containing protein.
    
 0.986
Vbra_11898
ERCC4 domain-containing protein.
    
 0.908
Vbra_17560
ERCC4 domain-containing protein.
    
 0.903
Vbra_23338
Uncharacterized protein.
  
 0.802
Vbra_11163
Uncharacterized protein.
  
 0.802
Vbra_12956
Uncharacterized protein.
  
 0.802
Vbra_20961
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 0.802
Vbra_4178
Uncharacterized protein.
  
 0.802
Vbra_5734
Uncharacterized protein.
  
 0.802
Vbra_15540
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 0.802
Your Current Organism:
Vitrella brassicaformis
NCBI taxonomy Id: 1169540
Other names: V. brassicaformis CCMP3155, Vitrella brassicaformis CCMP3155
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