STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMC1AStructural maintenance of chromosomes protein. (1233 aa)    
Predicted Functional Partners:
SMC3
Structural maintenance of chromosomes protein.
   
0.999
RAD21
Double-strand-break repair protein rad21 homolog.
   
 0.999
STAG2
Cohesin subunit SA-2 isoform X1.
   
 0.999
STAG1
Cohesin subunit SA-1 isoform X1.
   
 0.998
NIPBL
Nipped-B protein.
   
 0.997
ESPL1
Separin.
   
 0.975
LOC113240795
Cohesin subunit SA-2-like.
   
 0.961
SMC1B
Structural maintenance of chromosomes protein.
  
 
0.953
RAD21L1
Double-strand-break repair protein rad21-like protein 1 isoform X1.
   
 0.952
PDS5A
Sister chromatid cohesion protein PDS5 homolog A.
   
 0.941
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.