STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)    
Predicted Functional Partners:
CRTAP
Cartilage-associated protein.
   
 0.927
P3H1
Prolyl 3-hydroxylase 1 isoform X1.
   
 0.918
P4HB
Protein disulfide-isomerase.
   
 0.768
PDIA4
Protein disulfide-isomerase A4.
   
 0.735
P3H4
Endoplasmic reticulum protein SC65.
   
 0.714
TBL3
Transducin beta-like protein 3 isoform X1.
   
 
 0.686
HSPA5
Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family.
 
 
 0.676
WDR36
LOW QUALITY PROTEIN: WD repeat-containing protein 36.
   
 
 0.668
PDIA2
Protein disulfide-isomerase A2.
   
 0.657
HSP90B1
Endoplasmin.
   
 0.645
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.