node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACVR1B | ACVR2A | A0A3Q7VXZ8 | A0A3Q7V911 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.961 |
ACVR1B | SMAD2 | A0A3Q7VXZ8 | A0A3Q7VST8 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.985 |
ACVR1B | SMAD3 | A0A3Q7VXZ8 | A0A3Q7V8H5 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.983 |
ACVR1B | SMAD4 | A0A3Q7VXZ8 | A0A3Q7VT07 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.766 |
ACVR1B | TGFBR1 | A0A3Q7VXZ8 | A0A3Q7XHE1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.440 |
ACVR1B | TGFBR2 | A0A3Q7VXZ8 | A0A3Q7VKE6 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.766 |
ACVR1B | ZFYVE9 | A0A3Q7VXZ8 | A0A3Q7UY35 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Zinc finger FYVE domain-containing protein. | 0.474 |
ACVR2A | ACVR1B | A0A3Q7V911 | A0A3Q7VXZ8 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.961 |
ACVR2A | SMAD2 | A0A3Q7V911 | A0A3Q7VST8 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.967 |
ACVR2A | SMAD3 | A0A3Q7V911 | A0A3Q7V8H5 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.966 |
ACVR2A | SMAD4 | A0A3Q7V911 | A0A3Q7VT07 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.748 |
ACVR2A | TGFBR1 | A0A3Q7V911 | A0A3Q7XHE1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.953 |
ACVR2A | ZFYVE16 | A0A3Q7V911 | A0A3Q7WJY3 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Zinc finger FYVE domain-containing protein 16 isoform X1. | 0.437 |
ACVR2A | ZFYVE9 | A0A3Q7V911 | A0A3Q7UY35 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Zinc finger FYVE domain-containing protein. | 0.541 |
E2F4 | SMAD2 | A0A3Q7WJX9 | A0A3Q7VST8 | Transcription factor E2F4. | Mothers against decapentaplegic homolog. | 0.967 |
E2F4 | SMAD3 | A0A3Q7WJX9 | A0A3Q7V8H5 | Transcription factor E2F4. | Mothers against decapentaplegic homolog. | 0.979 |
E2F4 | SMAD4 | A0A3Q7WJX9 | A0A3Q7VT07 | Transcription factor E2F4. | Mothers against decapentaplegic homolog. | 0.974 |
FOXO1 | SMAD2 | A0A3Q7V9Z4 | A0A3Q7VST8 | Forkhead box protein O1. | Mothers against decapentaplegic homolog. | 0.975 |
FOXO1 | SMAD3 | A0A3Q7V9Z4 | A0A3Q7V8H5 | Forkhead box protein O1. | Mothers against decapentaplegic homolog. | 0.975 |
FOXO1 | SMAD4 | A0A3Q7V9Z4 | A0A3Q7VT07 | Forkhead box protein O1. | Mothers against decapentaplegic homolog. | 0.735 |