STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB116Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (101 aa)    
Predicted Functional Partners:
DEFB129
LOW QUALITY PROTEIN: beta-defensin 129.
     
 0.776
DEFB123
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.734
DEFB113
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
  
  
 0.712
DEFB124
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.653
LOC113258454
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.637
IL22RA2
Interleukin-22 receptor subunit alpha-2.
      
 0.594
DEFB127
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.562
LOC113261013
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.553
LOC113261014
Beta-defensin 110-like.
     
 0.553
DEFB134
Beta-defensin 134.
  
  
  0.478
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.