STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABRAActin-binding Rho-activating protein. (380 aa)    
Predicted Functional Partners:
GOSR1
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
      
 0.592
ITGB1BP2
Integrin beta-1-binding protein 2 isoform X1.
   
  
 0.558
ABLIM2
Actin-binding LIM protein 2 isoform X1.
    
 
 0.530
MYOZ2
Myozenin-2.
   
    0.522
FLRT3
Leucine-rich repeat transmembrane protein FLRT3.
      
 0.506
LOC113270935
Actin-related protein T1-like; Belongs to the actin family.
   
 
 0.506
SETD7
Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
      
 0.504
ABLIM3
Actin-binding LIM protein 3 isoform X3.
    
 
 0.470
LRRC10
Leucine-rich repeat-containing protein 10.
   
  
 0.442
ABRACL
Costars family protein ABRACL isoform X2.
      
 0.439
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.