STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCOA2Nuclear receptor coactivator. (1464 aa)    
Predicted Functional Partners:
RXRB
Retinoic acid receptor RXR-beta isoform X1.
   
 0.995
NCOA1
Nuclear receptor coactivator.
  
0.995
ESR1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
    
 0.993
RXRA
Retinoic acid receptor RXR-alpha isoform X1.
   
 0.990
CREBBP
CREB-binding protein isoform X1.
   
 0.974
NCOA3
Nuclear receptor coactivator.
  
0.967
EP300
Histone acetyltransferase p300.
   
 0.966
KAT6A
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 0.949
AR
Androgen receptor.
    
 0.948
RXRG
Retinoic acid receptor RXR-gamma isoform X1.
   
 0.948
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.