STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACP4Testicular acid phosphatase; Belongs to the histidine acid phosphatase family. (450 aa)    
Predicted Functional Partners:
AMBN
Ameloblastin.
      
 0.599
LOC113243079
Cytochrome P450 26A1; Belongs to the cytochrome P450 family.
    
 
 0.529
SSUH2
Protein SSUH2 homolog isoform X1.
      
 0.529
RDH10
Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.512
ITPA
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
      
 0.510
CSF3R
Granulocyte colony-stimulating factor receptor isoform X1.
      
 0.510
AMTN
Amelotin isoform X1.
      
 0.506
SDR16C5
Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.506
LOC113248311
Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.502
SLC24A1
Sodium/potassium/calcium exchanger 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.489
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.