STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC6Coiled-coil domain-containing protein 6. (476 aa)    
Predicted Functional Partners:
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
     
 0.948
NCOA4
Nuclear receptor coactivator 4 isoform X1.
     
 0.941
CCDC120
Coiled-coil domain-containing protein 120 isoform X2.
      
 0.724
SRRM2
Serine/arginine repetitive matrix protein 2 isoform X1.
      
 0.717
PDXDC1
Pyridoxal-dependent decarboxylase domain-containing protein 1 isoform X1.
      
 0.715
CCDC68
Coiled-coil domain-containing protein 68.
      
 0.714
NIN
Ninein isoform X1.
      
 0.592
PPP4C
Serine/threonine-protein phosphatase.
    
 
 0.589
CCDC106
Coiled-coil domain-containing protein 106 isoform X1.
      
 0.584
THRAP3
Thyroid hormone receptor-associated protein 3.
      
 0.527
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
Server load: low (24%) [HD]