STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2068 aa)    
Predicted Functional Partners:
KCTD6
BTB/POZ domain-containing protein KCTD6.
      
 0.943
SPRYD3
SPRY domain-containing protein 3 isoform X1.
    
 
 0.940
ASPM
Abnormal spindle-like microcephaly-associated protein.
   
  
 0.837
ANLN
Anillin.
   
 0.823
FBXO45
F-box/SPRY domain-containing protein 1.
      
 0.745
USP7
Ubiquitin carboxyl-terminal hydrolase 7 isoform X1; Belongs to the peptidase C19 family.
    
 
 0.730
PRC1
Protein regulator of cytokinesis 1 isoform X1.
   
 0.684
KIF14
Kinesin-like protein KIF14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.656
KIF20A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.599
MYO9A
Unconventional myosin-IXa isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  0.594
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.