STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (445 aa)    
Predicted Functional Partners:
PDPK1
3-phosphoinositide-dependent protein kinase 1.
  
 
0.990
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.986
NEDD4L
E3 ubiquitin-protein ligase NEDD4-like isoform X1.
   
 0.981
FOXO1
Forkhead box protein O1.
    
 0.946
FOXO3
Forkhead box protein O3.
    
 0.935
FOXO4
Forkhead box protein O4.
    
 0.925
FOXO6
Forkhead box protein O6.
    
 0.925
RICTOR
Rapamycin-insensitive companion of mTOR isoform X1.
    
 0.925
KCNJ1
ATP-sensitive inward rectifier potassium channel 1.
     
 0.924
LOC113268043
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
  
 
 
0.907
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.