STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CH25HCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (270 aa)    
Predicted Functional Partners:
LOC113268059
25-hydroxycholesterol 7-alpha-hydroxylase isoform X1; Belongs to the cytochrome P450 family.
   
 0.990
LOC113267281
Cholesterol 24-hydroxylase; Belongs to the cytochrome P450 family.
   
 0.971
LOC113268152
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 0.968
LOC113250446
Sterol 26-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family.
   
 0.957
LOC113259854
Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family.
   
 0.939
HSD3B7
3 beta-hydroxysteroid dehydrogenase type 7 isoform X2.
   
 0.939
SC5D
Lathosterol oxidase; Belongs to the sterol desaturase family.
   
 
 0.933
DHCR7
7-dehydrocholesterol reductase.
   
 0.929
SQLE
Squalene monooxygenase.
   
 
 0.910
DHCR24
Delta(24)-sterol reductase.
   
 
 0.898
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.