STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC12Coiled-coil domain-containing protein 12. (166 aa)    
Predicted Functional Partners:
CDC40
pre-mRNA-processing factor 17.
    
  0.996
PRPF19
pre-mRNA-processing factor 19.
    
   0.961
CDC5L
Cell division cycle 5-like protein isoform X1.
    
   0.941
EFTUD2
116 kDa U5 small nuclear ribonucleoprotein component.
    
   0.933
SRRM1
Serine/arginine repetitive matrix protein 1 isoform X1.
     
 0.933
PPIL1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.930
PPIL2
RING-type E3 ubiquitin-protein ligase PPIL2.
   
 0.922
CWC27
Spliceosome-associated protein CWC27 homolog.
   
 0.922
DHX38
pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16.
    
  0.917
SRRM2
Serine/arginine repetitive matrix protein 2 isoform X1.
   
 
  0.917
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.