STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEPHS2Selenide, water dikinase 2. (447 aa)    
Predicted Functional Partners:
SEPSECS
O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis.
     
 0.973
SCLY
Selenocysteine lyase isoform X1.
    
 0.950
TXNRD3
Thioredoxin reductase 3 isoform X2.
  
 
 0.943
TXNRD2
Thioredoxin reductase 2, mitochondrial.
  
 
 0.939
TXNRD1
Thioredoxin reductase 1, cytoplasmic isoform X2.
  
 
 0.937
SEPHS1
Selenide, water dikinase 1 isoform X1.
  
  
 
0.901
MOCOS
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
    
 0.687
EEFSEC
Selenocysteine-specific elongation factor isoform X1.
     
 0.614
SELENOO
Selenoprotein O.
     
 0.598
LOC113246289
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
      
 0.597
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.