STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC113259669Protein LEG1 homolog. (298 aa)    
Predicted Functional Partners:
HOGA1
4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1; Belongs to the DapA family.
   
  
 0.601
CCDC127
Coiled-coil domain-containing protein 127.
      
 0.595
CFAP61
Cilia- and flagella-associated protein 61.
      
 0.595
ATP6V1FNB
Protein ATP6V1FNB.
      
 0.595
TMED1
Transmembrane emp24 domain-containing protein 1 isoform X1.
      
 0.581
DOK2
Docking protein 2 isoform X3.
      
 0.561
MMACHC
Methylmalonic aciduria and homocystinuria type C protein isoform X1.
   
  
 0.535
KIAA0408
Uncharacterized protein KIAA0408 homolog isoform X1.
      
 0.511
RNF146
E3 ubiquitin-protein ligase RNF146.
      
 0.510
SPPL3
Signal peptide peptidase-like 3.
      
 0.510
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.