STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAP2CRas-related protein Rap-2c. (183 aa)    
Predicted Functional Partners:
RAPGEF2
Rap guanine nucleotide exchange factor 2 isoform X1.
   
 0.946
RHOA
Transforming protein RhoA.
  
0.927
ITSN2
Intersectin-2.
   
 0.802
ITSN1
Intersectin-1 isoform X3.
    
 0.712
RAPGEF4
Rap guanine nucleotide exchange factor 4 isoform X1.
    
 0.634
RAP1GAP
Rap1 GTPase-activating protein 1 isoform X4.
    
 0.578
MET
Hepatocyte growth factor receptor.
   
 0.560
MST1R
Macrophage-stimulating protein receptor isoform X1.
   
 0.560
NF1
Neurofibromin isoform X1.
   
 0.559
RAP1GAP2
Rap1 GTPase-activating protein 2 isoform X1.
    
 0.542
Your Current Organism:
Ursus arctos
NCBI taxonomy Id: 116960
Other names: U. arctos horribilis, Ursus arctos horribilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.