STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucDSuccinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (297 aa)    
Predicted Functional Partners:
sucC
Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
kgd
Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component.
 
 0.986
AFV89036.1
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase.
 0.970
AFV89646.1
Succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 0.961
AFV89917.1
Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.961
sdhA
Succinate dehydrogenase or fumarate reductase, flavoprotein subunit.
 
 0.956
AFV89918.1
Succinate dehydrogenase flavoprotein subunit.
 
 0.956
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.946
AFV90387.1
2-oxoglutarate oxidoreductase, alpha subunit.
  
 
 0.943
AFV88945.1
Methylmalonyl-CoA mutase.
    
 0.939
Your Current Organism:
Acidipropionibacterium acidipropionici
NCBI taxonomy Id: 1171373
Other names: A. acidipropionici ATCC 4875, Acidipropionibacterium acidipropionici ATCC 4875, Acidipropionibacterium acidipropionici DSM 20272, Acidipropionibacterium acidipropionici JCM 6432, Propionibacterium acidipropionici ATCC 4875, Propionibacterium acidipropionici DSM 20272, Propionibacterium acidipropionici JCM 6432
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.