STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDS46720.1tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. (350 aa)    
Predicted Functional Partners:
SDS46765.1
tRNA threonylcarbamoyl adenosine modification protein YeaZ.
 
 
 0.998
SDS46674.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
  0.987
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
 
 0.986
nnrD
yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specif [...]
  
 
 0.850
SDR93434.1
Alanine racemase.
 
 
  0.762
trmD
tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
 
 
 0.757
SDS46790.1
Ribosomal-protein-alanine N-acetyltransferase.
  
 
 0.749
SDR78275.1
N-succinyldiaminopimelate aminotransferase.
    
  0.714
SDS42912.1
Hypothetical protein.
    
  0.714
SDS44190.1
Aspartate/methionine/tyrosine aminotransferase.
    
  0.714
Your Current Organism:
Actinopolymorpha singaporensis
NCBI taxonomy Id: 117157
Other names: A. singaporensis, Actinopolymorpha singaporensis Wang et al. 2001 emend. Nouioui et al. 2018, Actinosingapura polymorpha, DSM 22024, JCM 10761, NBRC 100040, NRRL B-24113, strain IM 7744
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