STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nadK-2NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (350 aa)    
Predicted Functional Partners:
SDS91258.1
23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase.
  
  
 0.938
SDS14131.1
NAD(P) transhydrogenase subunit alpha.
     
 0.934
SDS14191.1
NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.931
SDS91203.1
DNA replication and repair protein RecN.
  
 0.928
SDS14154.1
NAD(P) transhydrogenase subunit alpha.
     
 0.915
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.910
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.910
nadE-3
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.898
SDT09404.1
NAD-dependent deacetylase.
     
 0.843
SDS91292.1
Hypothetical protein.
       0.791
Your Current Organism:
Actinopolymorpha singaporensis
NCBI taxonomy Id: 117157
Other names: A. singaporensis, Actinopolymorpha singaporensis Wang et al. 2001 emend. Nouioui et al. 2018, Actinosingapura polymorpha, DSM 22024, JCM 10761, NBRC 100040, NRRL B-24113, strain IM 7744
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