SDT06084.1 protein (Actinopolymorpha singaporensis)

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second shell of interactors

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

SDT06084.1

Protein of unknown function. (328 aa)

Predicted Functional Partners:

SDR83493.1

0.914

SDS53076.1

0.905

SDS92570.1

0.732

acpP

0.709

SDT13157.1

0.687

SDS69203.1

0.686

SDS79394.1

0.676

SDS29877.1

0.667

SDR91362.1

0.652

SDT17178.1

0.650

Your Current Organism:

Actinopolymorpha singaporensis

NCBI taxonomy Id: 117157
Other names: A. singaporensis, Actinopolymorpha singaporensis Wang et al. 2001 emend. Nouioui et al. 2018, Actinosingapura polymorpha, DSM 22024, JCM 10761, NBRC 100040, NRRL B-24113, strain IM 7744

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDR83493.1	SDT06084.1	SAMN04489717_0738	SAMN04489717_4883	Peptidase inhibitor I9; Belongs to the peptidase S8 family.	Protein of unknown function.	0.914
SDR91362.1	SDS29877.1	SAMN04489717_1005	SAMN04489717_2248	Hypothetical protein.	Oxidoreductase family, NAD-binding Rossmann fold; Manually curated.	0.768
SDR91362.1	SDS69203.1	SAMN04489717_1005	SAMN04489717_3542	Hypothetical protein.	Predicted dehydrogenase.	0.769
SDR91362.1	SDS79394.1	SAMN04489717_1005	SAMN04489717_3894	Hypothetical protein.	Predicted dehydrogenase.	0.671
SDR91362.1	SDS92570.1	SAMN04489717_1005	SAMN04489717_4371	Hypothetical protein.	Hypothetical protein.	0.648
SDR91362.1	SDT06084.1	SAMN04489717_1005	SAMN04489717_4883	Hypothetical protein.	Protein of unknown function.	0.652
SDR91362.1	SDT13157.1	SAMN04489717_1005	SAMN04489717_5151	Hypothetical protein.	Oxidoreductase family, NAD-binding Rossmann fold.	0.770
SDS29877.1	SDR91362.1	SAMN04489717_2248	SAMN04489717_1005	Oxidoreductase family, NAD-binding Rossmann fold; Manually curated.	Hypothetical protein.	0.768
SDS29877.1	SDS79394.1	SAMN04489717_2248	SAMN04489717_3894	Oxidoreductase family, NAD-binding Rossmann fold; Manually curated.	Predicted dehydrogenase.	0.729
SDS29877.1	SDS92570.1	SAMN04489717_2248	SAMN04489717_4371	Oxidoreductase family, NAD-binding Rossmann fold; Manually curated.	Hypothetical protein.	0.764
SDS29877.1	SDT06084.1	SAMN04489717_2248	SAMN04489717_4883	Oxidoreductase family, NAD-binding Rossmann fold; Manually curated.	Protein of unknown function.	0.667
SDS53076.1	SDT06084.1	SAMN04489717_2988	SAMN04489717_4883	Endoglucanase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	Protein of unknown function.	0.905
SDS69203.1	SDR91362.1	SAMN04489717_3542	SAMN04489717_1005	Predicted dehydrogenase.	Hypothetical protein.	0.769
SDS69203.1	SDS79394.1	SAMN04489717_3542	SAMN04489717_3894	Predicted dehydrogenase.	Predicted dehydrogenase.	0.681
SDS69203.1	SDS92570.1	SAMN04489717_3542	SAMN04489717_4371	Predicted dehydrogenase.	Hypothetical protein.	0.760
SDS69203.1	SDT06084.1	SAMN04489717_3542	SAMN04489717_4883	Predicted dehydrogenase.	Protein of unknown function.	0.686
SDS79394.1	SDR91362.1	SAMN04489717_3894	SAMN04489717_1005	Predicted dehydrogenase.	Hypothetical protein.	0.671
SDS79394.1	SDS29877.1	SAMN04489717_3894	SAMN04489717_2248	Predicted dehydrogenase.	Oxidoreductase family, NAD-binding Rossmann fold; Manually curated.	0.729
SDS79394.1	SDS69203.1	SAMN04489717_3894	SAMN04489717_3542	Predicted dehydrogenase.	Predicted dehydrogenase.	0.681
SDS79394.1	SDS92570.1	SAMN04489717_3894	SAMN04489717_4371	Predicted dehydrogenase.	Hypothetical protein.	0.706

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

20

average node degree:

3.64

avg. local clustering coefficient:

0.797

expected number of edges:

10

PPI enrichment p-value:

0.00519

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006865

Amino acid transport

6 of 55

1.91

3.07

8.56e-08

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042597

Periplasmic space

6 of 98

1.66

2.51

2.37e-07

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6087

Mixed, incl. Branched-chain amino acid transport, and Nickel cation binding

5 of 36

2.02

2.7

1.99e-06

CL:7456

Mixed, incl. GAF-ANTAR transcription anti-termination regulator, putative, and STAS domain

3 of 6

2.57

2.18

9.16e-05

CL:6089

Mixed, incl. Branched-chain amino acid transport, and Branched-chain amino acid ATP-binding cassette transporter, C-terminal

4 of 26

2.06

2.17

4.30e-05

CL:6091

Branched-chain amino acid transport, and Branched-chain amino acid ATP-binding cassette transporter, C-terminal

3 of 15

2.17

1.75

0.00044

CL:6092

Branched-chain amino acid transport, and Branched-chain amino acid ATP-binding cassette transporter, C-terminal

2 of 10

2.17

0.92

0.0197

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

6 of 491

0.96

0.75

0.0024

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0042597

Periplasmic space

6 of 191

1.37

1.56

2.51e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13433

Periplasmic binding protein domain

3 of 3

2.87

2.45

3.28e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR028081

Leucine-binding protein domain

4 of 4

2.87

3.72

1.39e-07

IPR028082

Periplasmic binding protein-like I

6 of 51

1.94

3.12

8.74e-08

IPR012074

GAF-ANTAR transcription anti-termination regulator, putative

3 of 4

2.75

2.36

4.69e-05

IPR005561

ANTAR domain

3 of 5

2.65

2.34

4.69e-05

IPR003018

GAF domain

4 of 28

2.03

2.13

4.69e-05

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01012

ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.

3 of 5

2.65

2.57

1.72e-05

SM00065

Domain present in phytochromes and cGMP-specific phosphodiesterases.

4 of 34

1.94

2.26

1.72e-05

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